MULTIMODAL REGULATION ORCHESTRATES NORMAL AND COMPLEX DISEASE STATES IN THE RETINA



Bakuchiol and Ethyl (Linoleate/Oleate) Synergistically Modulate Endocannabinoid Tone in Keratinocytes and Repress Inflammatory Pathway mRNAs

The endocannabinoid (eCB) system plays an active role in epidermal homeostasis.Phytocannabinoids such as cannabidiol Figure Skating - Skates - Girls modulate this system but also act through eCB-independent mechanisms.This study evaluated the effects of cannabidiol, bakuchiol (BAK), and ethyl (linoleate/oleate) (ELN) in keratinocytes and reconstitu

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C. elegans Heterochromatin Factor SET-32 Plays an Essential Role in Transgenerational Establishment of Nuclear RNAi-Mediated Epigenetic Silencing

Summary: The dynamic process by which nuclear RNAi engages a transcriptionally active target, before the repressive state is stably established, remains largely a mystery.Here, we found that the onset of exogenous dsRNA-induced nuclear RNAi in Cocoa Powder C.elegans is a transgenerational process, and it requires a putative histone methyltransferas

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